AAARRRGG! First they discontinue 4759, one of the best ever powders for Schuetzen style loadings, and now that they’re sure that powder is pretty much all gone, they discontinue arguably the second best powder for the purpose!  Are they trying to kill our game? 
Froggie

Is that H4227 and IMR4227?

Back around 2015, Hodgson transfered mfg. Of H4227 over to IMR...and dropped the H.  At the time I was concerned as that was my go to powder for .22 hornet and .38-55.  I spoke with them and was told the "new" IMR was in fact the original H4227 powder.
Just got off the phone  with Hodgdon....was assured that their IMR 4227 was not being discontinud.

So, the sky is not falling again?

Well, I’m old enough that I won’t be shooting many more years.  A four lb jug should last the rest of of my life (to go with the 6-8 lb of 4759 and the 20 lb of H-108). Ledball persuaded me to shoot some H-108 in 32-40 back in the day.  He said 4759 was a passing fad, not knowing how soon H-108 would disappear.  I guess between the three (or maybe just 2) I will have powder for as long as I’m able to shoot.
Froggie

I have found vihtavouri N110 to be cleaner burning and slightly more accurate in the .22 Hornet than H4227.

I don't understand the big fuss. There are better powders that measure excellent in a Harrels. As Randy mentioned 296 works good. 300MP is my go to powder for the 32-40. I guess my 8# metal can of 4227 from Canada is now worth a mint!

If you do a search for either H4227 or IMR 4227, you should come up with a old thread, from about 8 yrs ago.

It was documented in that thread, that Hodgdon replace IMR 4227 with the Australian made H4227 BUT, kept the IMR 4227 name. A profit oriented change.

At the end of the day I'm not convinced that a large conglomerate that controls the availability of a favorite powder to have my best interests at heart, no matter the assurances. The supply chain of our shooting "expendables" has proven time and again in the last 20 years to be unreliable, and fickle at best. I chose to err on the side of caution yesterday and ordered some 4227 to bolster my my small stash. Yes Chicken Little the sky is not falling but by golly there are some fairly big raindrops hitting the ground.

Other alternatives exist, sure, but personally I have more important things to worry about than starting another whole round of experiments to find which of said alternatives are equal to my old "tried and true".

Jim has left some jugs of smokeless powder H-108,XMR4350 and WC820(f).  Can someone tell me the differences in these powders?

Ordinarily this is a good resource for powder comparison, site is currently down for update and maintenance. 

It will have photos and measurements of powders, along with other information. It’s the justice department data base for forensic comparison and identification of powders.

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Thank you so much for your replies.  I have some things that should come back to the Assoc.  Plan on bringing when I get stuff together.

The Australian made ADI AR2205 powder is the equivalent of 4227. This is currently out of production with no anticipated new production or delivery date. Hogdon have previous purchased powder from ADI (Varget for example) so it makes sense that 4227 may be the same and is now in short/ non supply in the US as well.

Disappointing for all of us, regardless of US or AUS.