I have a Shiloh Sharps 45-70 with a new Soule midrange tang sight.  I would like to start my sight setting on at least a 4' X 4'
paper, and not have to chase and guess where my first shots are hitting at 50 yds.
Can anyone give me a close setting on the vertical adjustment on the sight to get me started when the snow goes and I can get to the range to start my initial settings?
Thanks

Or, set your rifle up in a rest and sight through the barrel and center the target. Then, without moving your rifle, adjust your tang sight to the same target. Then, double check both are on the target and you won't be far off when you shoot.
Chris types faster;-) But I would start with the barrel and then move the sight to match.

Found the book for my Sharps, I have a parts unknown '78 style sight on it. it is a souel sight. I dont have a 100 yd setting but for 200 its at .270", 300 is .460", 385 is .570" and 500.780". Those will give you some kind of a ball park to play in. I was shooting about 68gr of CTG Goex, and a 535 postel bullet. That bullet has constantly shot well for me. 
Sam

Oldbee, lots of folks get all in an uproar over finding a reasonable zero with a new or untried rifle. I used to. But after many years of shooting I doscovered the real procedure. You get a Repair Center target froma High power shooter. Most clubs have them. They are 22" X 20" square (I think) You post them at 25 yards. Now at this distance you almost just cannot miss it. Once you get a shot on you can make adjustments and walk your way into center, then crank the rear sight up so it is shooting 3" High at 25 yds and go from there, or less for 100 yds. Now you are on the paper. Lot of guy's spend a lot of time and ammo trying to conserve what? the more you shoot the better you will get with experience. Just keep working at it and enjoy. HTH Regards FITZ OLD TUCK.

Getting a 50 yard setting is likely going to be pretty hard with that sight.
But the quickest way to get close will be set the rifle on a bench in good bags or rest of some kind. Get the front sight centered as well as you can on the target, then drop the rear aperture until you can make out the front sight and the target at the lowest point on the slide.

Well, I might as well confuse the OP with another method for sighting in a rifle.   Get a large sheet of paper or cardboard and put a big cross on it. Use a magic marker so that you can see the cross OK.  Than set the target up 12 and a half yards from the muzzle of your rifle. You can't miss at that distance. Make sure your Soule is set on zero and your eyecup quite low, maybe around 20 minutes. Take a shot right at the center of the cross. Each 1/8" from the center of the cross is one minute. You can use that method to drift your front sight right or left until you're right on center with the cross you can adjust your elevation up and down until you're right on the cross. Shouldn't take more than a few shots.